FDA approves nasal spray to treat migraines, promising ‘efficacy on demand’

Impel NeuroPharma, a Seattle-based biopharmaceutical company, received approval from the U.S. Food and Drug Administration last week for its novel nasal spray that treats migraine headaches. The therapeutic, called Trudhesa, involves the use of Impel’s patented device called the POD, which sprays dihydroergotamine mesylate (DHE) into patients’ noses more precisely so it reaches the upper […]

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Mothers’ diabetes may induce premature aging of neural tissue in early development of fetuses, leading to birth defects

More than 3 million women of birthing age in the U.S. and 60 million in the world have diabetes—a disease that occurs when blood sugar is too high. Even when controlled with insulin, and blood sugar levels are kept mostly in check, maternal diabetes can cause permanent damage to the fetus. About 300,000 to 400,000 […]

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Balkan countries and Poland rank highest in lung cancer risk for ages 50 to 69, attributable to air pollution

Five European countries rank highest for lung cancer risk among those aged 50 to 69 years attributable to air pollution, according to research presented in today’s Presidential Symposium Plenary Session at the IASLC 2021 World Conference on Lung Cancer. Although tobacco smoke is clearly a major cause of lung cancer, a recent analysis determined that […]

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Omics data suggests larger effect of smoking on body mass index than previously thought

Smoking-related DNA methylation patterns explain around a fifth of the variation in body mass index (BMI) between individuals, according to a study publishing September 9th in the open-access journal PLOS Genetics, led by Carmen Amador at the University of Edinburgh. Amador and colleagues analyzed genomic sequence data from over 390,000 white British participants enrolled in […]

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